Psyche Machina

"You're Not Crazy": A Case of New-onset AI-associated Psychosis

Innovations in clinical neuroscience, 2025

L5of 5
Design
Case report
Risk of bias
High risk of bias
Sample
n = 1
AI type
General-purpose assistants
Outcomes
Psychosis
Authors' conclusion
“This case provides evidence that new-onset psychosis in the form of delusional thinking can emerge in the setting of immersive AI chatbot use. Although multiple pre-existing risk factors may be associated with psychosis proneness, the sycophancy of AI chatbots together with AI chatbot immersion and deification on the part of users may represent particular red flags for the emergence of AI-associated psychosis.”Quoted verbatim from the abstract.

Draft grade. Level and risk of bias were assigned by our agent and await expert review. How we grade

Read the paper →PMID 41635747